If you scroll through the aesthetic side of TikTok long enough, you’ll eventually see the phrase "salmon sperm facial." It sounds like clickbait. It sounds gross. But in the medical world, we call it PDRN therapy, and it's genuinely one of the most exciting breakthroughs we've had for skin rejuvenation in years.
I know, I know. It sounds wild. But if you're chasing that "glass skin" look, the kind where your skin texture looks filtered in real life, and your overall radiance is off the charts, this is how we can actually get there.
At SHarper Plastic Surgery, we don't jump on trends just because they are viral. We jump on them when the science holds up. And the science behind mixing microchanneling Botox and PDRN is solid. We call our version the GloTox Infusion Facial, and it's quickly becoming the secret weapon for our SHarper Babes who want youthful skin without looking "done."
Let’s clear up what this actually is. PDRN (Polydeoxyribonucleotide) is derived from salmon DNA. Specifically, the salmon's sperm.
Why salmon? It turns out their DNA is a near-perfect match to human DNA. Because of this biological similarity, polynucleotide therapy (another common name for PDRN) is incredibly well tolerated by our systems. Your body doesn't fight it or react negatively. Instead, your cells recognize it as a powerful healing agent.
Now, we're not just rubbing salmon sperm on your face and calling it a day. There's a process to extract the DNA from the sperm, which is then used in the microchannelling treatment. It's a lot less weird than it sounds online.
Originally, medicine used PDRN for joint repair and serious wound healing. But we realized that those same regenerative properties work miracles on the face. When we introduce it to the dermis, it acts on a cellular level by screaming at your skin cells to wake up and start working. It boosts collagen production, thickens the skin barrier, and accelerates tissue regeneration.
So, while hyaluronic acid (which we love) hydrates you temporarily, PDRN treatments are actually teaching your body to build better, stronger skin for the long haul.
Here's where we get fancy. I don’t just use PDRN alone. I mix it into a custom cocktail with a neurotoxin—usually Botox, Xeomin, or Daxxify.
When most people think of Botox, they think of freezing a muscle to stop a wrinkle. This is different. We aren't injecting it into the muscle. We're stamping it superficially into the skin layer.
When we use "Micro-Botox" this way, it does three incredible things for your skin health:
We deliver this "liquid gold" cocktail using a minimally invasive technique called microchanneling. I use a device with gold-plated needles thinner than a human hair to gently stamp the blend into your skin.
It creates microscopic channels that allow the growth factors from the salmon DNA and the pore-shrinking power of the Botox to penetrate deep into the dermis. This ensures the ingredients get exactly where they need to be to affect tissue repair and skin elasticity.
Because the injection sites are so tiny and superficial, the healing process is incredibly fast. You might look a little pink for a few hours, similar to a post-workout flush, but there is essentially minimal downtime. You aren't hiding in your house for a week peeling like you would with aggressive laser treatments.
I wanted to wrap this science in an experience that feels good, so we created the GloTox Infusion Facial. We don't just stamp you and send you out the door.
The procedure begins with a deep cleanse and dermaplaning. We remove the dead skin cells and peach fuzz to ensure the treatment area is primed to absorb every drop of the cocktail. Then, we apply a medical-grade topical numbing cream. We let that sit so the treatment is comfortable.
Once you are numb, we perform the microchanneling. Finally, we calm everything down with a cooling mask or LED therapy to reduce any initial redness. The whole process enhances skin texture to be smoother, sleek, and picture-perfect. You'll leave looking glazed, not battered.
The results are "high-gloss." You get that enhanced hydration and plumper skin almost immediately from the treatment itself, but the real magic happens over the next few weeks.
As the benefits of PDRN kick in and the Botox tightens the surface, you'll notice fine lines and wrinkles softening. Your skin tone evens out. That stubborn, uneven skin texture starts to smooth over. Because PDRN helps remodel tissue, it's even effective for treating acne scars and improving the look of stretch marks.
It significantly increases collagen production over time, meaning this is long-term rejuvenation.
Because this uses ingredients your body produces or recognizes easily, PDRN therapy's safe protocols apply to almost everyone. It's low risk and effective for all skin types, even sensitive skin that might not tolerate stronger lasers.
If you're dealing with early signs of aging, looking to minimize visible signs of sun damage, redness in the skin, or just want to fix that tired, gray, dull look, this is the answer.
Yes, it’s extracted from salmon sperm. Yes, it works. PDRN sessions are the future of skincare, and we are thrilled to bring them to Avon. If you want to see if this is right for your aesthetic goals, come see us. We offer a free aesthetic consultation to map out a plan for you.
